Approximately £15-40 per refill depending on size and supplier:

Cost breakdown:

20L Refill:      £15-25 (liquid nitrogen)
                 £5-10 (delivery)
                 Total: £20-35 per refill
50L Refill:      £25-40 (liquid nitrogen)
                 £10-15 (delivery)
                 Total: £35-55 per refill
100L+ Refill:    £40-75 (liquid nitrogen)
                 £15-25 (delivery)
                 Total: £55-100 per refill
Annual cost estimates:
20L:  £300-600/year
50L:  £300-600/year (fewer refills)
100L: £300-600/year (even fewer refills)

Cost-saving strategies:

  • Direct contract with gas supplier (save 15-25%)
  • Annual service contract (bundle refills + maintenance)
  • Facility sharing with other clinics
  • Bulk purchasing (if multiple units)