Vitrification is ultra-rapid freezing that turns cells into a glass-like solid without forming ice crystals, while controlled-rate freezing cools samples slowly and precisely along a programmed temperature curve. The two methods suit different tasks. Vitrification has become the preferred approach for eggs and embryos because of its very high survival rates, and it is one of the advances highlighted in the ESHRE 2026 study as a driver of modern IVF success.
Controlled-rate freezing remains important for other sample types, such as certain cells and tissues where a slow, uniform cooling profile protects them best. Many laboratories therefore use both methods, choosing the technique that matches the biology of the sample. Cryolab supplies both vitrification kits and controlled rate freezing equipment, so laboratories can standardise on the right tool for each application.
