Cryogenic technology encompasses the science, engineering, and applied methods involved in producing, managing, and using materials at temperatures below -150°C. It is one of the most consequential areas of applied science in modern medicine, underpinning everything from IVF and biobanking to MRI scanner operation, surgical oncology, and the emerging hydrogen energy economy.
In biological research and IVF specifically, cryogenic technology means one thing above all others: liquid nitrogen at -196°C and the vacuum-insulated vessels that contain it. The application of cryogenic temperature to biological material causes a transition to what scientists describe as the glassy state – a condition in which molecular motion effectively ceases and biological time stops. Below approximately -130°C, enzymatic activity and cellular metabolism halt completely. Biological samples stored correctly at cryogenic temperature do not degrade.
The practical impact of this on IVF medicine has been transformative. Vitrification, the ultra-rapid cooling technique now standard in accredited IVF laboratories, plunges embryos and oocytes into liquid nitrogen at rates fast enough to prevent ice crystal formation entirely. The global cryogenic storage equipment market was valued at USD 7.8 billion in 2025 and is projected to expand to USD 13.2 billion by 2034, growing at a CAGR of 6.8%, reflecting accelerating demand across biobanking, pharmaceutical development, and healthcare infrastructure worldwide.
Recent developments in cryogenic technology relevant to IVF laboratories include IoT-enabled continuous monitoring systems that track LN2 levels and storage temperatures remotely with out-of-hours alarm notifications, automated sample retrieval systems that reduce access event frequency and associated temperature excursions, and ultra-low nitrogen consumption vessel designs that extend static holding times and reduce LN2 supply dependency.
Cryolab supplies cryogenic storage technology for IVF laboratories, biobanks, and research institutions globally. Browse the full storage vessel range or contact the Cryolab team to discuss your requirements.